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Nick NolteNeal Cassady
Sissy SpacekCarolyn Cassady
John HeardJack Kerouac
Ray SharkeyIra
Ann DusenberryStevie
Margaret FairchildMrs. Kerouac
Tony BillDickMary Margaret AmatoWaitressKent WilliamsOgdenSusan NivenOgden's Secretary
Marcia NasatirFirst ReceptionistMickey KellySecond Receptionist
Luis ContrerasMexican JunkieSharon LeeBlonde in Car
John LarroquetteTV Talk Show Host
Terence H. WinklessYouth in Bar
Steve AllenHimself
David LynchPainterMickey KellySecond Receptionist
Raymond VitteUndercover Agent
