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Frank WelkerScooby-Doo / Fred Jones / Self
Matthew LillardNorville 'Shaggy' Rogers / Self - Voice of "Shaggy"
Grey DeLisleDaphne Blake / Self - Voice of "Daphne"
Kate MicucciVelma Dinkley / Self - Voice of "Velma"
Janel ParrishJanel Parrish - Host
Jerry BeckSelf - Animation Historian and Author
David SilvermanSelf - Director and Producer, "The Simpsons"
Seth GreenSelf - Actor, "Scooby-Doo 2: Monsters Unleashed"
Tony CervoneSelf - Director, "Scoob!" / Showrunner, "Mystery Incorporated"
Tom SitoSelf - Animator, Historian
Joseph BarberaSelf - Hanna-Barbera Co-Founder (archive footage)
Mary Lynn RajskubProducer Bryn
Baron VaughnBram Penobscot - Scooby's Vocal Coach
Casey KasemShaggy Rogers (voice) (archive footage)
Diedrich BaderBatman - Concerned Citizen (voice)
'Weird Al' YankovicSelf - Singer, Songwriter, Accordionist
Olivia LiangOlivia Liang - Shaggy's Martial Arts Trainer
Karamo BrownCostume Designer Carter
Mitch WatsonSelf - Showrunner, "Mystery Incorporated"
Cheri OteriLazlo the Mechanic
Brendan JenningsArlo Davidsonman - Team ScoobyVadym KrasnenkoSnow GhostLindsey AlenaAdditional Voices (voice)Dominic CatramboneAdditional Voices (voice)
Fred TatascioreAdditional Voices (voice)
