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Seth WeitbergHimself - NarratorBJ PorterHimself - Narrator
Georgia HardstarkHerself - Narrator
Alie WardHerself - Narrator
Tony HaleMeriwether Lewis
Taran KillamWilliam Clark
Kumail NanjianiLakota Chief
Aubrey PlazaSacagawea
Bradley WhitfordWilliam Jennings Bryan
Jack McBrayerClarence Darrow
Rich FulcherPorter Wagoner
Casey WilsonDolly PartonDakota BlackLakota IndianA.J. CulpJoleneJohn A. LorenzLakota IndianKyle David CrosbyScientistMichael KearneyIntervieweeLacie MadisonParty Guest
Michael Daniel CassadyVarious
Sarah BurnsVarious
Adam NeeVariousBennie ArthurVarious
Maria BlasucciVarious
Craig CackowskiVariousJeremy J. TutsonVarious
Tymberlee HillVarious
